EXCERPT from book: "... The reader may be sure, therefore, that I made attempts innumerable to reduce the quantity (((OF OPIUM))). I add, that those who witnessed the agonies of those attempts, and not myself, were the first to beg me to desist. But could not I have reduced it a drop a day, or by adding water, have bisected or trisected a drop?...
... that down to a certain point it can be reduced with ease and even pleasure, but, that after that point, further reduction causes intense suffering. ..."
Confessions of an English Opium-Eater
by Thomas de Quincey
Heritage Press - New York - 1950
Note: the original edition was published sometime in the 19th century.
(It's not upside down.)